Stereopsis in Macular Degeneration

Macular degeneration affects the central retina, often causing asymmetrical damage to the two eyes. How does this asymmetrical loss affect stereopsis — the percept of depth generated by the small separation of image features in the two eyes? We measured the largest separation between features in the two eyes that yields a percept of depth in humans. This upper separation limit successfully predicts  that individuals with retinal damage due to macular degeneration will have stereopsis when the separation between intact retinal locations in the two eyes is smaller than the upper disparity limit measured behaviorally, demonstrating the importance of the upper separation limit as a predictor for stereopsis in populations with retinal damage