Zoom Brown Bag: Normal and Disrupted Binocular Interactions in Human Striate and Extra-striate Visual Cortex

Abstract - I will describe recent studies in the lab on binocular interactions in striate and extra-striate visual cortex in normal and amblyopic vision. Using source-imaged SSVEP and frequency-domain analysis of dichoptic stimuli, we measured two forms of binocular interactions: one is associated with the individual stimuli that represent interocular suppression from each eye, and the other is a direct measure of interocular interaction between inputs from the two eyes. We have shown that both forms of binocular interactions share a common gain control mechanism in striate and extra-striate cortex. Furthermore, our model fits, revealed different patterns of binocular interaction along the visual cortical hierarchy, particularly in terms of excitatory and suppressive contributions in normal and amblyopic vision.

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